英语翻译A correlation of these structural data with cellular transfection efficiencies reveals that the highest transfection efficiency is obtained with those amphiphiles that are easily hydrated,form fluid aggregates,and undergo a transition to

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英语翻译A correlation of these structural data with cellular transfection efficiencies reveals that the highest transfection efficiency is obtained with those amphiphiles that are easily hydrated,form fluid aggregates,and undergo a transition to
英语翻译
A correlation of these structural data with cellular transfection efficiencies reveals that the highest transfection efficiency is obtained with those amphiphiles that are easily hydrated,form fluid aggregates,and undergo a transition to the inverted hexagonal phase in the presence of plasmid DNA(p-DNA)at physiological ionic strength.

英语翻译A correlation of these structural data with cellular transfection efficiencies reveals that the highest transfection efficiency is obtained with those amphiphiles that are easily hydrated,form fluid aggregates,and undergo a transition to
A correlation of these structural data with cellular transfection efficiencies reveals that the highest transfection efficiency is obtained with those amphiphiles that are easily hydrated,form fluid aggregates,and undergo a transition to the inverted hexagonal phase in the presence of plasmid DNA(p-DNA)at physiological ionic strength.
结构数据与细胞转染效率的关联性显示,易于水合的两亲化合物具有最高的转染效率,它可形成流体聚集体,并在生理离子强度以及质体DNA(p-DNA) 的存在下,发生向六角相的转变.
Cationic amphiphiles are considered promising alternatives for viral vectors in gene therapy due to the negligible immunogenicity,relative ease of large-scale production and amenability for structural modification.
一般认为,阳离子性两亲化合物在基因治疗中,可以作为病毒载体的绝佳替代物,这归因于以下三点:它几乎没有免疫原性;其规模化生产相对易于实现;其结构改性具有可控性.

这些关联结构化数据显示,随着蜂窝transfection效率最高的效率与transfection得到试剂,易保湿,形成流体的骨料、接受过渡到倒六角阶段质体DNA(的存在)p-DNA生理离子强度

Chemical